Solubility and Dissolution Enhancement of Tadalafil Using Self-Nanoemulsifying Drug Delivery System
نویسندگان
چکیده
منابع مشابه
Formulation and Evaluation of Self microemulsifying drug delivery system of low solubility drug for enhanced solubility and dissolution
Atorvastatin is a BCS class II lipid lowering agent. It is insoluble in aqueous solution of pH 4 and below; it is very slightly soluble in water and pH 7.4 phosphate buffer. In the present investigation an attempt has been made to enhance solubility and dissolution of poorly soluble drug by formulating self microemulsifying drug delivery system (SMEDDS). The solubility of atorvastatin in indivi...
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BACKGROUND Self-nanoemulsifying drug delivery systems (SNEDDS) have become a popular formulation option as nanocarriers for poorly water-soluble drugs. The objective of this study was to investigate the factor that can influence the design of successful lipid formulation classification system (LFCS) Type III SNEDDS formulation and improve the oral bioavailability (BA) of fenofibrate. MATERIAL...
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ژورنال
عنوان ژورنال: Journal of Oleo Science
سال: 2014
ISSN: 1345-8957,1347-3352
DOI: 10.5650/jos.ess13236